GLP-1 + Sermorelin
GLP-1 is the most effective weight-loss therapy available — but rapid loss can strip lean muscle along with fat. This protocol pairs GLP-1 with sermorelin to restore your natural growth-hormone rhythm, helping preserve lean mass and recovery while the weight comes off.
Same day prescription
FDA-regulated pharmacies
US-licensed longevity doctors
FSA/HSA eligible
10,000+ people exploring health with us
What's in this protocol:
GLP-1
Physician-prescribed GLP-1 therapy — your provider selects semaglutide or tirzepatide based on your health profile.
Sermorelin
A GHRH analog that prompts the pituitary to release growth hormone in its natural, pulsatile rhythm — studied for body composition, recovery and sleep quality.
Lose fat and hold onto muscle.
GLP-1 drives the weight loss
By acting on your appetite hormones, GLP-1 therapy produces the largest, best-evidenced weight loss of any injectable — the engine of this protocol.
Sermorelin helps preserve lean muscle
Rapid weight loss risks taking lean mass with the fat. Sermorelin restores your natural growth-hormone pulse, which supports muscle maintenance, recovery and sleep during a calorie deficit.
One physician, one coordinated plan
Your Chia physician doses and monitors both compounds as one plan — GLP-1 titration and sermorelin are adjusted together, never as two disconnected prescriptions.
How it works
Take the 2-min health quiz
Provider reviews & approves
Compound is prepared & shipped
Track & optimize with your doctor
Every batch tested
U.S.-licensed
Regulated sources
Uncover Your Longevity Potential
Getting started is risk-free. We'll track your labs — 40+ biomarkers — reviewed by a licensed provider to personalize your plan.
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Frequently asked questionsquestions
It's our flagship weight-loss stack: your GLP-1 (semaglutide or tirzepatide) drives the fat loss while sermorelin helps you keep your muscle. GLP-1 acts on your appetite hormones to produce the largest, best-evidenced weight loss of any injectable. Rapid loss risks stripping lean mass along with fat, so sermorelin restores your natural growth-hormone pulse to support muscle maintenance, recovery and sleep during the calorie deficit.
Rapid weight loss risks taking lean mass with the fat. Sermorelin prompts your pituitary to release growth hormone in its natural, pulsatile rhythm — over 16 weeks in adults aged 55–71, nightly GHRH raised IGF-1 and added lean muscle in the men (J Clin Endocrinol Metab, 1997). It supports the muscle maintenance, recovery and deeper sleep a calorie deficit tends to undermine.
Your GLP-1 (semaglutide or tirzepatide) is the engine — it reduces appetite to produce the weight loss, with semaglutide averaging 14.9% body-weight loss over 68 weeks (New England Journal of Medicine, 2021). Sermorelin restores your natural growth-hormone rhythm to help preserve lean muscle, aid recovery from training, and support deeper, more restorative slow-wave sleep.
The two evidence tiers differ, and we're honest about that. GLP-1 weight loss rests on some of the largest, most rigorous trials in metabolic medicine. Sermorelin's human studies are smaller and older, pointing more to how it works — restoring GH pulses to support lean mass and sleep — than to proven long-term outcomes. Together they pair a proven weight-loss engine with muscle-preservation support.
Yes. Your Chia physician doses and monitors both compounds as one plan — GLP-1 titration and sermorelin are adjusted together, never as two disconnected prescriptions. All Chia clinicians are US-licensed. After your intake, a clinician reviews your profile, typically within 24 hours, and you keep ongoing portal access for progress tracking and questions at no extra cost.
Both compounds are FSA/HSA eligible — pay with your HSA/FSA card at checkout. You can cancel anytime through your portal; before your consultation, before your first shipment, or if you're found ineligible, you get a full refund. Month-to-month plans include a 30-day satisfaction guarantee. See chia.health/legal/refund-policy for full details.