GHK-Cu CreamRebuild your skin. A cream that works.
A copper-peptide cream you apply at home, studied for collagen, firmness and skin remodeling — no injection required.
Same day prescription
FDA-regulated sources
US-licensed physicians
FSA/HSA eligible
GHK-Cu Cream works even harder in combination
Most patients who take GHK-Cu Cream have more than one goal. These physician-curated protocols pair it with other compounds — supervised by one physician, delivered as one plan.
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GHK-Cu Cream benefitsGHK-Cu Cream treatment benefits
Studied for collagen synthesis and skin firmness
Supports wound healing and skin remodeling
Associated with favorable shifts in skin gene expression
Topical cream — applied at home, no injection required
How it works
Take the 2-min health quiz
Provider reviews & approves
Compound is prepared & shipped
Track & optimize with your doctor
Every batch tested
U.S.-licensed
Regulated sourcesThe science behind GHK-Cu
GHK-Cu is a natural copper peptide your skin uses to renew and repair itself. Decades of lab and animal work plus smaller human skin trials back it — it's a skincare ingredient, not a whole-body drug.
Boosts collagen
In lab-grown skin cells, GHK-copper ramped up collagen production even at very low amounts (FEBS Letters, 1988).
Broad gene-expression modulation
In a gene-mapping analysis, GHK shifted the activity of a large share of human genes, including dozens tied to DNA repair (International Journal of Molecular Sciences, 2018).
Wound healing and antioxidants
In animal studies, GHK-Cu applied to the skin sped wound healing and raised protective antioxidant levels in the tissue (BioMed Research International, 2015).
Declines with aging
Your natural GHK levels drop by more than half between ages 20 and 60 — alongside slower tissue repair (Aging Pathobiology and Therapeutics, 2020).
Clinically validated. Physician monitored.
GHK-Cu is a natural copper peptide your skin uses to renew and repair itself. Decades of lab and animal work plus smaller human skin trials back it — it's a skincare ingredient, not a whole-body drug.
Boosts collagen
In lab-grown skin cells, GHK-copper ramped up collagen production even at very low amounts (FEBS Letters, 1988).
Broad gene-expression modulation
In a gene-mapping analysis, GHK shifted the activity of a large share of human genes, including dozens tied to DNA repair (International Journal of Molecular Sciences, 2018).
Wound healing and antioxidants
In animal studies, GHK-Cu applied to the skin sped wound healing and raised protective antioxidant levels in the tissue (BioMed Research International, 2015).
Declines with aging
Your natural GHK levels drop by more than half between ages 20 and 60 — alongside slower tissue repair (Aging Pathobiology and Therapeutics, 2020).
What patients are saying
4.9 out of 5 from 256 reviews
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
"I'm 64 and the backs of my hands were my tell. After half a year they look less papery, and I'm vain enough to celebrate that."
Lorraine V.
"An old acne scar on my temple has softened to where I stopped angling away from cameras. Topical, painless, zero-drama routine."
Imani F.
"Thirty years of ranch sun left my forearms looking older than the rest of me. They've evened out noticeably since fall. I'm not chasing youth, just repair."
Cass B.
"I work the cosmetics counter, so I've tried everything with a peptide on the label. This is the one that finally earned a permanent spot on my shelf. The lines around my mouth are noticeably softer, month three."
Juliet K.
"The crepey skin on my neck bothered me more than any wrinkle. Six months of nightly application and it's visibly firmer. The photo from January lives on my phone for skeptical friends."
Glenda P.
"I'm 54 and gave up on serum promises a decade ago. By week eight the texture on my cheeks was different enough that I stopped using the blurring filter on work calls."
Francine L.
Individual results may vary.
Frequently asked questions
GHK-Cu is a naturally occurring copper-binding peptide, delivered here as a topical cream you apply at home. It's studied for collagen synthesis, skin firmness, and remodeling — your natural GHK levels drop by more than half between ages 20 and 60, alongside slower tissue repair (Aging Pathobiology and Therapeutics, 2020). Most people look for visible changes in texture and firmness over 8 to 12 weeks.
The evidence is real but measured. In lab-grown skin cells, GHK-copper ramped up collagen production even at very low amounts (FEBS Letters, 1988), and in animal studies it sped wound healing and raised protective antioxidant levels (BioMed Research International, 2015). In a small skin-biopsy study (about 10 people per group), a copper-peptide cream raised procollagen in more people than vitamin C or a retinoid (Abdulghani et al., 1998) — this is early, small-sample data, not proof it beats any prescription treatment. In a gene-mapping analysis it shifted a large share of human genes, including dozens tied to DNA repair (International Journal of Molecular Sciences, 2018). It's a well-studied skincare ingredient, not a whole-body drug — we describe it honestly.
It's a topical cream applied to clean skin daily, in the morning and/or evening as your physician directs — no injection required. Because it works gradually as your skin remodels collagen, consistency matters more than amount. Your physician reviews your skin goals and profile and confirms how to layer it with the rest of your routine.
Yes. GHK-Cu Cream is the aesthetic centerpiece of our Glow (Skin Renewal) protocol, where it's paired with glutathione and NAD+ — the cream rebuilds collagen at the surface while glutathione brightens tone and NAD+ powers cellular repair from within. You can also use the cream on its own. Your physician prescribes and monitors whichever fits your goals.
It's suited to people focused on firmer, brighter, younger-looking skin — collagen, texture and tone. Copper peptides are generally well tolerated topically; your physician screens for copper allergy and reviews your history before prescribing. To start, take the 2-minute health quiz and a licensed US clinician reviews your profile, typically within 24 hours.
GHK-Cu Cream may be FSA/HSA eligible with a valid prescription — check with your plan administrator. Pay with your HSA/FSA card at checkout and email support@chia.health if your administrator needs documentation. You can cancel anytime through your patient portal. Before your consultation, before your first shipment, or if you're found ineligible, you get a full refund; we also offer a 30-day money-back refund on unused monthly plans. Details at chia.health/legal/refund-policy.
